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The implications of clonal genome evolution for cancer medicine

​Aparicio S et al

N Engl J Med. 2013 Feb 28;368(9):842-51

 

Summary

Large-scale DNA sequencing of cancer genomes has provided insight into the clonality of tumor cells, in addition to potential targets for new therapeutic approaches. This review article discusses how methods to detect tumor-cell clonality may come to inform clinical practice.


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